Table 3.
Gene ontology, biological processes enriched in differentially methylated regions associated with 12-month AOSI score
Rank | GOBPID | P-value | Odds ratio | Expected Count | Count | Size | Term |
---|---|---|---|---|---|---|---|
1 | GO:0006928 | 0.00027 | 3.55 | 5.0 | 14 | 1495 | Cellular component movement |
2 | GO:0040011 | 0.00035 | 3.61 | 4.5 | 13 | 1344 | Locomotion |
3 | GO:0030155 | 0.00045 | 6.86 | 1.0 | 6 | 297 | Regulation of cell adhesion |
4 | GO:0007155 | 0.00139 | 3.57 | 3.3 | 10 | 989 | Cell adhesion |
5 | GO:0022610 | 0.00143 | 3.56 | 3.3 | 10 | 993 | Biological adhesion |
6 | GO:0051056 | 0.00161 | 5.31 | 1.3 | 6 | 380 | Regulation of small gtpase mediated signal transduction |
7 | GO:0022008 | 0.00226 | 3.15 | 4.2 | 11 | 1242 | Neurogenesis |
8 | GO:0048011 | 0.00231 | 5.96 | 0.9 | 5 | 278 | Neurotrophin TRK receptor signaling pathway |
9 | GO:0038179 | 0.00242 | 5.89 | 0.9 | 5 | 281 | Neurotrophin signaling pathway |
10 | GO:0007626 | 0.00244 | 7.77 | 0.6 | 4 | 169 | Locomotory behavior |
11 | GO:0008543 | 0.00325 | 7.15 | 0.6 | 4 | 183 | Fibroblast growth factor receptor signaling pathway |
12 | GO:0044344 | 0.00462 | 6.46 | 0.7 | 4 | 202 | Cellular response to fibroblast growth factor stimulus |
13 | GO:0071774 | 0.00478 | 6.39 | 0.7 | 4 | 204 | Response to fibroblast growth factor |
14 | GO:0048699 | 0.00485 | 2.96 | 3.9 | 10 | 1173 | Generation of neurons |
15 | GO:0007264 | 0.00618 | 3.99 | 1.7 | 6 | 499 | Small gtpase mediated signal transduction |
16 | GO:0007399 | 0.00647 | 2.52 | 6.2 | 13 | 1848 | Nervous system development |
17 | GO:0051235 | 0.00653 | 5.83 | 0.7 | 4 | 223 | Maintenance of location |
18 | GO:0007173 | 0.00663 | 5.80 | 0.8 | 4 | 224 | Epidermal growth factor receptor signaling pathway |
19 | GO:0009894 | 0.00687 | 3.47 | 2.3 | 7 | 675 | Regulation of catabolic process |
20 | GO:0007265 | 0.00695 | 5.72 | 0.8 | 4 | 227 | Ras protein signal transduction |
21 | GO:0038127 | 0.00706 | 5.70 | 0.8 | 4 | 228 | ERBB signaling pathway |
22 | GO:0007268 | 0.00726 | 3.44 | 2.3 | 7 | 682 | Synaptic transmission |
23 | GO:0007411 | 0.00748 | 4.47 | 1.2 | 5 | 367 | Axon guidance |
24 | GO:0097485 | 0.00748 | 4.47 | 1.2 | 5 | 367 | Neuron projection guidance |
25 | GO:0051674 | 0.00802 | 3.37 | 2.3 | 7 | 695 | Localization of cell |
26 | GO:0050790 | 0.00841 | 2.50 | 5.7 | 12 | 1688 | Regulation of catalytic activity |
27 | GO:0030182 | 0.00891 | 2.84 | 3.6 | 9 | 1081 | Neuron differentiation |
GOBPID, Gene Ontology Biological Processes ID.