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. 2015 Oct 9;5:14959. doi: 10.1038/srep14959

Figure 4. Effects of chronic inflammation and rapamycin on glucose and insulin tolerance in vivo.

Figure 4

The C57BL/6J mice fed with a high-fat diet (HFD) were randomly assigned to receive a subcutaneous injection of normal saline, casein, casein plus vehicle and casein plus rapamycin. (a) Glucose tolerance tests (glucose-stimulated blood glucose concentrations, IGTT) performed after 14 weeks of treatment. (b) Insulin tolerance tests (insulin-stimulated blood glucose concentrations, IITT) performed at the end of the experiments. The results represent the mean ± SD (n = 6). * P < 0.05 versus control. #P < 0.05 versus casein plus vehicle group.