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. 2015 Oct 9;5:14917. doi: 10.1038/srep14917

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LPS: lipopolysaccharides; PMA: phorbol-12-myristate-13-acetate; fMLP: N-formyl-methionyl-leucyl-phenylalanine; MYD88: myeloid differentiation primary response gene 88; TIRAP: Toll-interleukin 1 receptor (TIR) domain containing adaptor protein; PKC: protein kinase C; DAG: diacyl-glycerol; RAC-1: Ras-related C3 botulinum toxin substrate 1; PIP3: phosphatidylinositol (3,4,5)-triphosphate; PIP2: phosphatidylinositol 4,5-bisphosphate; PLC: phospholipase C; MAPK: mitogen-activated protein kinase; Tyr-Kinase: tyrosine kinase; CDC42 Rac: cell division control protein 42 homolog; C-Src: tyrosine-protein kinase CSK.