Figure 2. Increased susceptibility to N. caninum infection in CD8a^−/− mice.

Parasitic load of brain and lungs tissue assessed by qPCR specific for N. caninum DNA in WT or CD8a^−/− mice, as indicated, 7 days after i.p. inoculation of 1 × 10⁷ NcT. Bars represent means plus one SD of pooled data from two independent experiments (n = 10 for controls and n = 12 for infected mice). Unpaired two-tailed t-test was used to compare parasite-inoculated vs respective control mouse groups. Statistical significance between infected mice and controls is indicated above bars.