Figure 7. Protective effect of adoptively transferred Ifng^+/+ CD8⁺ T cells in N. caninum-infected Rag2^−/− mice.

Parasitic load in brain and lung tissue assessed by qPCR 7 days after i.p. infection with 1 × 10⁷ NcT of Rag2^−/− mice or Rag2^−/− mice reconstituted with WT CD4⁺ T cells and CD8⁺ T cells sorted from WT or Ifng^−/− mice, as indicated. Bars represent means plus one SD. Statistical significance between the different mouse groups (one-way ANOVA and Tukey’s post-hoc test) is indicated above bars (n = 4 for non-reconstituted Rag2^−/− mice and n=  10 per reconstituted group).