Figure 3.

Immunohistochemical localization of ?-catenin in normal oral mucosa (A-B), in which only membrane expression is observed; mild dysplasia (C-D), where the protein is mainly localized at membrane and cytoplasm and the nuclear expression is present but at the lowest degree (D). Immunohistochemical localization of ?-catenin in moderate dysplasia (E-F), where the nuclear expression of ?-catenin is greater; severe dysplasia (G-H) where the protein strongly expressed at the lower layers of the epithelium.