Table 2.
Final diagnoses obtained from each group (IFF/Fiocruz-INCA, RJ, Brazil, 2006–2012)
| Pap smear diagnosis n (%) | Total | |||
|---|---|---|---|---|
| Final diagnosisa | HSIL microh | HSILc | p-value | |
| Negative | 0 (0) | 24 (12.8) | 24 (10.2) | 0.005 |
| LSILb | 2 (4.3) | 28 (14.9) | 30 (12.8) | 0.052 |
| HSILc | 15 (31.9) | 112 (59.6) | 127 (54) | <0.001 |
| AISd | 0 (0) | 2 (1.1) | 2 (0.9) | 1.000 |
| Microinvasive lesione | 6 (12.8) | 10 (5.3) | 16 (6.8) | 0.070 |
| Invasive lesionf | 19 (40.4) | 9 (4.8) | 28 (11.9) | <0.001 |
| Adenocarcinomag | 5 (10.6) | 3 (1.6) | 8 (3.4) | 0.009 |
| Total (%) | 47 (100) | 188 (100) | 235 (100) | |
aDiagnoses obtained at the end of investigation considering histopathological specimens. Negative cases were based on absence of visible colposcopic findings and two negative cytopathologic exams with a minimum of six-month intervals
bLow-grade squamous intraepithelial lesion (includes cytopathic effect by HPV and CIN 1)
cHigh-grade squamous lesion (includes CIN 2 and CIN 3)
dAdenocarcinoma in situ
eMicroinvasive squamous carcinoma of the cervix
fInvasive squamous carcinoma of the cervix
gInvasive squamous adenocarcinoma of the cervix
hHigh-grade intraepithelial lesion cannot exclude microinvasion