Table 3.

Prevalence of preinvasive or invasive disease by study group (IFF/Fiocruz-INCA, RJ, Brazil, 2006–2012)

Final diagnosisa	Preinvasive or invasive lesionb	Absence of preinvasive or invasive lesionc	Total n (%)	Prevalence Ratio (PR) (CI 95 %)
Pap smear diagnosis
HSIL-Microd	45	2	47	6.5 (1.6 - 25.7)
HSILe	136	52	188	<0.001
Total	181	54	235

^aRecategorized diagnoses obtained at the end of investigation considering histopathological specimens. Negative cases were based on absence of visible colposcopic findings and two negative cytopathologic exams with a minimum of six-month intervals

^bIncludes CIN 2, CIN 3, adenocarcinoma in situ and microinvasive or invasive squamous carcinoma of the cervix

^cIncludes negative diagnoses, HPV cytopathic effect and CIN 1

^dHigh-grade intraepithelial lesion cannot exclude microinvasion

^eHigh-grade intraepithelial lesion