Table 4.

Prevalence of invasive disease by study group (IFF/Fiocruz-INCA, RJ, Brazil, 2006–2012)

Final diagnosisa	Invasive lesionb	Absence of invasive lesionc	Total n (%)	Prevalence Ratio (PR) (CI 95 %)
Pap smear diagnosis
HSIL-microd	30	17	47	2.4 (1.7 – 3.6)
HSILe	22	166	188	<0.001
Total	52	183	235	-

^aRecategorized diagnoses obtained at the end of investigation considering histopathological specimens. Negative cases were based on absence of visible colposcopic findings and two negative cytopathologic exams with a minimum of six-month intervals

^bIncludes microinvasive squamous carcinoma of the cervix

^cIncludes negatives, CIN 1, 2 or 3, or AIS

^dHigh-grade intraepithelial lesion cannot exclude microinvasion

^eHigh-grade intraepithelial lesion