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Correlation of inhibition of receptor phosphorylation to receptor quantitation. A, IC50 values for JNJ-61186372-mediated inhibition of EGFR phosphorylation plotted versus EGFR ABC. Pearson correlation method results are p = 0.0074 and r2 = 0.7903. B, IC50 values for JNJ-61186372-mediated inhibition of c-MET phosphorylation plotted versus c-MET ABC. Pearson correlation method results are p < 0.0001 and r2 = 0.9331.
