Table 1.
Effect of subacute exposure to safranal (SAF i.p. for 3 weeks) on mice blood cellularity and splenocyte enumeration.
| Parameter | Vehicle control | SAF 0.1ml/kg | SAF 0.5 ml/kg | SAF 1ml/kg | Cyclophosphamide |
|---|---|---|---|---|---|
| Blood WBC (cell/µl) | 9190 ± 388 | 9250 ± 235 | 8240 ± 454 | 8700 ± 498 | 4750 ± 132*** |
| Blood neutrophil (cell/µl) | 1976 ± 156 | 1610 ± 118 | 1505 ± 153 | 1949 ± 123 | 2270 ± 140 |
| Bood lymphocyte (cell/µl) | 7029 ± 247 | 7500 ± 209 | 6555 ± 363 | 6603 ± 484 | 2346 ± 205*** |
| Blood monocyte (cell/µl) | 184 ± 8 | 140 ± 11 | 179 ± 14 | 148 ± 17 | 133 ± 11** |
| Spleen cell content (×10 7 ) | 8.52 ± 1.36 | 6.68 ± 0.88 | 8.16 ± 1.33 | 6.12 ± 0.59 | 5.77 ± 1.52 |
Data showed as mean ± SEM.
**
P < 0.01 indicates significant changes compared to the vehicle control group.
***
P < 0.001 indicates significant changes compared to the vehicle control group.