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. 2015 Jun 25;13(8):1479–1493. doi: 10.1111/jth.13022

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© 2015 The Authors. Journal of Thrombosis and Haemostasis published by Wiley Periodicals, Inc. on behalf of International Society on Thrombosis and Haemostasis.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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The role of thromboxane A₂ (TxA₂) formation in primer-mediated rescue of the effect of antiplatelet drugs. (A) Insulin-like growth factor-1 (IGF-1). (B) Thrombopoietin (TPO). (C) Epinephrine. TxA₂ production was assessed with a thromboxane B₂ (TxB₂) ELISA with releasates generated from the samples shown in Fig.2A–D). Data are presented as mean ± standard error of the mean, n = 3–4. Statistical analysis: two-way anova was used in conjunction with a Bonferroni post hoc test; **P < 0.01, ***P < 0.001. ARC, AR-C66096; ASA, acetylsalicylic acid.