Table 3. Percent change between control vs. CTX animals.
| Measurement | Androgen Status | Day 1 | Day 3 | Day 5 | Day 7 |
|---|---|---|---|---|---|
| Muscle Weight | Normal (Intact) |
+20%* (CTX > Ctrl) |
-12%* (CTX < Ctrl) |
-20.4%* | -16.7%* |
| Depleted (GDX) | +24%* | -12.9%* | -14.3%* | -22.8%* | |
| HGF | Normal (Intact) | +67% | +364%* | +194%* | +107%* |
| Depleted (GDX) | +163%* | +527%* | +143%* | +105%* | |
| IGF-1 | Normal (Intact) | -50%* | -43%* | +4% | +34% |
| Depleted (GDX) | -38%* | -18% | +5% | +22% | |
| FST | Normal (Intact) | -45%* | -56%* | -28%* | -20%* |
| Depleted (GDX) | -44%* | -71%* | -44%* | +3% | |
| CXCR4 | Normal (Intact) | +116%* | +176%* | +80%* | +76%* |
| Depleted (GDX) | +19% | +71%* | +47%* | +106%* | |
| TNF-α | Normal (Intact) | +1294%* | -4% | +8% | -18% |
| Depleted (GDX) | +1752%* | +304%* | +54% | +52% |
Weight (body and muscle) and gene changes were compared between the Control versus CTX muscles in androgen-normal (intact) and androgen-depleted (GDX) animals, as displayed in Figure 4 (e.g., Normal Muscle Weight on Day 1 of +20% indicates CTX muscles were 20% heavier than Control muscles). *p>0.05; differences calculated to be significant, as shown graphically in Figure 4.