Table 2. Relationship between C/EBPβ protein expression and Clinicopathological features in HCC tissues.
| C/EBPβ immunostaining | ||||
|---|---|---|---|---|
| Clinicopathological Features | Number of cases | Score 0 N (%) |
Score 1 N (%) |
p Value |
| Age (years) | ||||
| <60 | 159 | 100(69.44) | 59(64.84) | 0.462 |
| ≥60 | 76 | 44(30.56) | 32(35.16) | |
| Gender | ||||
| Male | 190 | 109(75.69) | 81(88.04) | 0.020* |
| Female | 46 | 35(24.31) | 11(11.96) | |
| Tumor size | ||||
| ≤5cm | 113 | 72(51.80) | 41(45.55) | 0.356 |
| >5cm | 116 | 67(48.20) | 49(54.45) | |
| AFP (ng/ml) | ||||
| ≤20 | 79 | 42(29.79) | 37(40.66) | 0.088 |
| >20 | 153 | 99(70.21) | 54(59.34) | |
| HBV infection | ||||
| Negative | 42 | 30(21.43) | 12(13.48) | 0.130 |
| Positive | 187 | 110(78.57) | 77(86.52) | |
| Cirrhosis | ||||
| Absent | 38 | 19(13.20) | 19(20.65) | 0.128 |
| Present | 198 | 125(86.80) | 73(79.35) | |
| Edmondson's grade | ||||
| I, II | 119 | 61(42.36) | 58(63.04) | 0.002* |
| III, IV | 117 | 83(57.64) | 34(36.96) | |
| Intrahepatic metastasis | ||||
| Absent | 161 | 92(63.89) | 69(75.00) | 0.074 |
| Present | 75 | 52(36.11) | 23(25.00) | |
AFP, alpha-fetoprotein. N, Number of cases. P value represents the probability from a Chi-square test for different immunohistochemical scores of C/EBPβ in HCC tissues.
*
p<0.05.