Table 2.
Comparison of all the tests against the reference PCR method
| PCR +ve | PCR −ve | Total | ||
|---|---|---|---|---|
| LAMP +ve | 120 | 7 | 127 | Sn = 91.6 % (95 % CI 85.5–95.7); Sp = 96.7 % (95 % CI 93.3–98.7) |
| LAMP −ve | 11 | 203 | 214 | PPV = 94.5 % (95 % CI 89.1–97.8); NPV = 94.9 % (95 % CI 91.1–97.4) |
| κ = 0.91 (95 % CI 0.84-0.94) | ||||
| Mx +ve | 102 | 2 | 104 | Sn = 77.9 % (95 % CI 70.1–84.7); Sp = 99.1 % (95 % CI 96.6–99.9) |
| Mx −ve | 29 | 208 | 237 | PPV = 98.1 % (95 % CI 93.2–99.8); NPV = 87.8 % (95 % CI 82.9–91.7) |
| κ = 0.80 (95 % CI 0.73-0.87) | ||||
| RDT +ve | 100 | 26 | 126 | Sn = 76.3 % (95 % CI 68.1–83.3); Sp = 87.6 % (95 % CI 82.4–91.8) |
| RDT −ve | 31 | 184 | 215 | PPV = 79.4 % (95 % CI 71.3–86.1); NPV = 85.6 % (95 % CI 80.2–90.1) |
| κ = 0.64 (95 % CI 0.56-0.73) | ||||
| Total | 131 | 210 | 341 |
Sn sensitivity, Sp specificity, κ Kappa coefficient, PPV positive predictive value, NPV negative predictive value