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. Author manuscript; available in PMC: 2015 Oct 9.
Published in final edited form as: Pharmacogenomics J. 2014 Dec 23;15(4):340–346. doi: 10.1038/tpj.2014.76

Figure 2.

Figure 2

FK506 binding protein 5 (FKBP5) genotype and mRNA expression are associated with the acute response to IV nicotine. The association of FKBP5 rs3800373 genotype (left panels) and FKBP5 mRNA (right panels) to subjective reports of “negative” drug effects (A) and heart rate (B). For the graph, subjects were grouped as having high (n=24) or low (n=24) FKBP5 expression based on a median split. The mean value for each experimental condition is presented (±s.e.m.) and main effects of FKBP5 mRNA or genotype and interactive effects with dose are shown. Nic = nicotine.