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. Author manuscript; available in PMC: 2015 Oct 9.
Published in final edited form as: Pharmacogenomics J. 2014 Dec 23;15(4):340–346. doi: 10.1038/tpj.2014.76

Figure 3.

Figure 3

FK506 binding protein 5 (FKBP5) mRNA expression is positively correlated with cortisol levels. Effects were tested for (A) rs3800373 genotype (AA versus C-carrier) and (B) FKBP5 mRNA (graphed as high or low based on a median split). Time points are, 1. Post-IV line insertion; 2. Pre-saline injection; 3. Pre-nicotine (0.5 mg/70 kg) injection; 4. Pre-nicotine (1.0 mg/70 kg) injection and 5. Post-infusions. FKBP5 mRNA levels were obtained prior to time point 2. The mean value is presented (±s.e.m.) and main effects of FKBP5 mRNA or genotype and interactive effects with time point are shown. *Pairwise p <0.005. Nic=nicotine.