Table 2.
Months on Antiretroviral Therapy | Cohorts, N |
Participants, N |
Descriptive Statistics |
Random-Effects Meta-analysis |
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Total | Total | Median | Interquartile Range |
Median | Interquartile Range |
Summary Estimate | 95% Confidence Interval |
τ2a | ||||
Q1 | Q3 | Q1 | Q3 | Low | High | |||||||
On-treatment analysis | ||||||||||||
6 | 100 | 116 051 | 173 | 84 | 453 | 87.2 | 78.7 | 91.3 | 84.9 | 83.5 | 86.3 | 0.03 |
12 | 117 | 103 632 | 174 | 78 | 427 | 87.7 | 80.8 | 91.9 | 85.6 | 84.4 | 86.9 | 0.04 |
24 | 45 | 39 694 | 203 | 78 | 475 | 86.0 | 80.5 | 91.9 | 84.4 | 82.0 | 86.9 | 0.05 |
36 | 21 | 18 729 | 373 | 163 | 980 | 90.1 | 82.5 | 93.6 | 88.5 | 85.5 | 91.4 | 0.06 |
48 | 13 | 4673 | 201 | 104 | 384 | 90.9 | 85.1 | 94.6 | 88.6 | 84.2 | 93.0 | 0.09 |
60 | 6 | 1433 | 117 | 60 | 505 | 86.6 | 78.6 | 94.1 | 85.2 | 76.6 | 93.9 | 0.09 |
Intention-to-treat analysis | ||||||||||||
6 | 40 | 47 838 | 106 | 40 | 371 | 72.9 | 63.8 | 82.3 | 74.7 | 72.2 | 77.2 | 0.02 |
12 | 67 | 40 938 | 153 | 66 | 351 | 71.9 | 59.6 | 77.6 | 67.3 | 63.6 | 71.0 | 0.10 |
24 | 23 | 6332 | 142 | 66 | 321 | 65.0 | 52.4 | 72.2 | 64.6 | 60.8 | 68.4 | 0.03 |
36 | 4 | 1411 | 309 | 160 | 546 | 63.0 | 61.3 | 75.1 | 68.1 | 58.0 | 78.2 | 0.03 |
48 | 4 | 504 | 130 | 66 | 187 | 59.0 | 51.4 | 72.4 | 61.8 | 44.0 | 79.7 | 0.13 |
a τ2 is a measure of between-study heterogeneity that is less affected by the number of studies than other common measures.