Table 1.
Patients With Positive Lyme Disease Test Results by 2-Tier IgG Criteria
| Patient Sex | Clinical Presentationa | Alternative Diagnosis | Geographic Exposure |
|---|---|---|---|
| Male | Arthralgias | … | … |
| Male | Polyarthralgias | Celiac-associated joint pain | … |
| Male* | Facial nerve palsy | Connecticut | |
| Male* | Knee effusion | Maryland | |
| Male | Arthralgia, history of Lyme disease | Repetitive stress | … |
| Male* | Arthritis | … | |
| Male | Chronic pain | … | … |
| Female | Fever, urticaria, hand swelling | Allergic drug reaction | … |
| Female | Fever, headache, fatigue, negative CSF results | … | … |
| Female | Visual field loss | Retinal lesions | … |
| Male | High fever while in Southeast Asia | … | … |
| Male | Trigeminal neuralgia | … | … |
| Male* | Polyarthritis, sausage digit | … | |
| Male | Skin lesions | Eosinophilic lichenoid dermatitis | … |
| Male | Cranial nerve III palsy | Metastatic cancer to cavernous sinus | … |
| Male | Uveitis | … | … |
| Male* | Knee effusion and TMJ crepitus | … |
Abbreviations: CSF, cerebrospinal fluid; IgG, immunoglobulin G; TMJ, temporomandibular joint.
a Arthralgia was defined as joint pain or stiffness without documentation of joint effusion or inflammation; arthritis, as joint pain or stiffness with such documentation. Cases judged as “true positive” are marked with an asterisk (*).