Table 3.
Cardiopulmonary Test and Noninvasive Hemodynamics According to Functional and Ventilatory Classes
| Weber-Janicki classes | A (n=10) | B (n=54) | C (n=98) | D (n=28) |
|---|---|---|---|---|
| Peak VO2, mL/kg/min | 22.5±0.9 | 17.8±1.2 | 13.4±1.5 | 9.3±1.3 |
| Oxygen pulse, mL/beat | 14.7±3.3 | 12.5±3.1 | 10.0±2.7 | 8.2±2.7* |
| Resting PETCO2, mm Hg | 36.1±4.7 | 33.1±4.0 | 32.9±4.9 | 31.7±5.5* |
| VE/VCO2 slope | 31.8±3.9 | 35.4±4.2 | 36.9±3.2 | 38.9±6.9* |
| TFC, 1/KΩ | 36.0±2.9 | 36.7±5.2 | 37.8±3.1 | 39.3±9.2* |
| Stroke volume resting, mL | 85.5±17.8 | 68.0±3.6 | 70.6±23.3 | 70.4±16.9 |
| Arena et al classes | 1 (n=15) | 2 (n=84) | 3 (n=80) | 4 (n=11) |
|---|---|---|---|---|
| Peak VO2, mL/kg/min | 17.0±4.5 | 14.9±3.7 | 14.3±3.1 | 11.7±3.3† |
| Oxygen pulse, mL/beat | 12.2±2.7 | 11.4±3.3 | 10.1±3.0 | 9.5±2.2† |
| Resting PETCO2, mm Hg | 37.3±2.8 | 35.1±3.2 | 30.8±3.8 | 27.8±3.1‡ |
| VE/VCO2 slope | 26.8±2.1 | 33.0±1.6 | 39.8±2.9 | 48.2±2.2‡ |
| TFC, 1/KΩ | 31.3±4.1 | 34.6±5.3 | 39.7±5.7 | 45.9±6.1‡ |
| Stroke volume resting, mL | 78.1±19.5 | 77.9±24.2 | 68.1±19.5 | 50.1±13.6† |
Data are expressed as mean±1 SD. PETCO2, end-tidal CO2 pressure; TFC indicates transthoracic conductance;VE/VCO2, minute ventilation-to-carbon dioxide production; VO2, oxygen consumption per unit time.
*
P<0.05 Weber-Janicki class D vs Weber-Janicki class A (ANOVA with Bonferroni correction).
†
P<0.05 Arena et al class 4 vs either Arena et al class 1 or class 2 (ANOVA with Bonferroni correction).
‡
P<0.05 each of the Arena et al classes compared with the others (ANOVA with Bonferroni correction).