Table 3.
HRs of Cardiovascular Disease According to Body Mass Index and Metabolic Health Including Women With Diabetes*
| White | Black | Hispanic | ||||
|---|---|---|---|---|---|---|
| n=7508 | n=6043 | n=2802 | ||||
| Metabolic Abnormalities | HR | CI | HR | CI | HR | CI |
| Normal weight | ||||||
| 0 to 2 | Ref | — | Ref | — | Ref | — |
| 3 | 1.96 | 1.41 to 2.73 | 3.60 | 1.76 to 7.36 | 2.62 | 1.02 to 6.68 |
| ≥4 | 2.57 | 1.76 to 3.75 | 6.51 | 2.98 to 14.21 | 3.30 | 1.09 to 9.98 |
| Overweight | ||||||
| 0 to 1 | 0.79 | 0.57 to 1.11 | 0.99 | 0.55 to 1.79 | 0.48 | 0.16 to 1.42 |
| 2 | 0.99 | 0.76 to 1.30 | 1.59 | 0.99 to 2.54 | 1.34 | 0.63 to 2.85 |
| 3 | 1.15 | 0.87 to 1.51 | 1.81 | 1.10 to 2.98 | 0.83 | 0.35 to 2.01 |
| ≥4 | 1.89 | 1.49 to 2.37 | 3.29 | 2.03 to 5.31 | 2.30 | 1.15 to 4.58 |
| Obese | ||||||
| 0 to 1 | 1.02 | 0.64 to 1.63 | 1.18 | 0.60 to 2.32 | 1.51 | 0.51 to 4.49 |
| 2 | 1.05 | 0.77 to 1.44 | 1.84 | 1.18 to 2.88 | 0.68 | 0.23 to 2.04 |
| 3 | 1.12 | 0.85 to 1.49 | 2.69 | 1.77 to 4.08 | 2.07 | 1.04 to 4.11 |
| ≥4 | 1.96 | 1.60 to 2.40 | 3.21 | 2.09 to 4.91 | 1.53 | 0.74 to 3.20 |
All models were adjusted for age, smoking, and hormone use at baseline and stratified by hormone therapy trial study arm and hysterectomy status. HR indicates hazard ratio.
*
Women with diabetes were categorized as having an abnormal glucose metabolism regardless of fasting glucose levels.