Table 4.
HRs of Cardiovascular Disease According to Body Mass Index and Metabolic Health Defining Impaired Glucose Metabolism as Fasting Glucose ≥110 mg/dL in a Cohort of Postmenopausal Women
| White | Black | Hispanic | ||||
|---|---|---|---|---|---|---|
| n=6741 | n=5102 | n=2521 | ||||
| Metabolic Abnormalities | HR | CI | HR | CI | HR | CI |
| Normal weight | ||||||
| 0 to 2 | Ref | — | Ref | — | Ref | — |
| 3 | 1.75 | 1.18 to 2.59 | 2.81 | 1.09 to 7.29 | 3.11 | 1.14 to 8.54 |
| ≥4 | 3.02 | 1.97 to 4.64 | 11.02 | 4.23 to 28.69 | 1.47 | 0.19 to 11.22 |
| Overweight | ||||||
| 0 to 1 | 0.72 | 0.52 to 1.00 | 0.96 | 0.53 to 1.72 | 0.76 | 0.32 to 1.84 |
| 2 | 1.07 | 0.82 to 1.38 | 1.61 | 1.00 to 2.59 | 1.18 | 0.53 to 1.81 |
| 3 | 1.17 | 0.88 to 1.55 | 2.11 | 1.25 to 3.58 | 0.96 | 0.40 to 2.32 |
| ≥4 | 1.76 | 1.33 to 2.33 | 1.29 | 0.57 to 2.95 | 1.81 | 0.75 to 4.37 |
| Obese | ||||||
| 0 to 1 | 0.87 | 0.55 to 1.37 | 1.18 | 0.61 to 2.28 | 2.02 | 0.79 to 5.15 |
| 2 | 1.05 | 0.77 to 1.42 | 1.73 | 1.11 to 2.71 | 0.53 | 0.16 to 1.81 |
| 3 | 1.24 | 0.94 to 1.64 | 2.56 | 1.61 to 4.07 | 1.45 | 0.66 to 3.12 |
| ≥4 | 1.84 | 1.45 to 2.35 | 2.47 | 1.39 to 4.37 | 1.50 | 0.58 to 3.84 |
All models were adjusted for age, smoking, and hormone use at baseline and stratified by hormone therapy trial study arm and hysterectomy status. HR indicates hazard ratio.