Table 5.
HRs of Cardiovascular Disease in a Cohort of Postmenopausal Women According to BMI and Metabolic Health Using a Different Categorization*
| White | Black | Hispanic | ||||
|---|---|---|---|---|---|---|
| n=6741 | n=5102 | n=2521 | ||||
| Binary Model | HR | CI | HR | CI | HR | CI |
| Metabolically healthy* | ||||||
| Normal weight | Ref | — | Ref | — | Ref | — |
| Overweight | 1.05 | 0.81 to 1.37 | 1.54 | 0.95 to 2.52 | 1.30 | 0.60 to 2.78 |
| Obese | 1.25 | 0.92 to 1.69 | 1.85 | 1.15 to 3.00 | 1.13 | 0.44 to 2.91 |
| Metabolically unhealthy† | ||||||
| Normal weight, WC <80 cm | 2.09 | 1.54 to 2.82 | 1.24 | 0.50 to 3.05 | 3.17 | 1.32 to 7.61 |
| Normal weight, WC ≥80 cm‡ | 2.60 | 1.84 to 3.67 | 6.18 | 3.00 to 12.73 | 2.05 | 0.56 to 7.44 |
| Overweight, WC <80 cm | 1.18 | 0.65 to 2.14 | 0.88 | 0.26 to 2.95 | 1.69 | 0.47 to 6.03 |
| Overweight, WC ≥80 cm‡ | 1.66 | 1.31 to 2.12 | 1.88 | 1.11 to 3.19 | 1.32 | 0.59 to 2.96 |
| Obese‡ | 1.74 | 1.38 to 2.20 | 2.46 | 1.53 to 3.94 | 1.88 | 0.89 to 3.98 |
BMI indicates body mass index; HR, hazard ratio; WC, waist circumference.
*
Metabolically healthy defined as having <2 metabolic abnormalities.
†
Metabolically unhealthy defined as having ≥2 metabolic abnormalities.
‡
Metabolically unhealthy obese: obese (WC ≥80 cm or BMI ≥30) and ≥2 additional metabolic abnormalities.