Table 1.
Reactivity of Anti-p305 Autoantibody in Peripheral Blood of Healthy Controls, Research Registry for Neonatal Lupus Mothers, Lupus Patients, and Cord Blood of Healthy and Neonatal Lupus Children
| Group | N | Ro60% Positive | p305% Positive | p133-Ro60% Positive |
|---|---|---|---|---|
| Healthy controls | 55 | 0 | 2 | 0 |
| CHB mothers | 59 | 100 | 5 | 11 |
| Unaffected sibling mothers but previous or subsequent CHB | 30 | 87 | 13 | 17 |
| Anti-Ro+ SLE mothers | 42 | 100 | 0 | ND |
| Anti-Ro− SLE mothers | 41 | 0 | 0 | ND |
| Healthy cord bloods | 5 | 0 | 0 | 0 |
| CHB neonates | 61 | 94 | 20 | 19 |
| Unaffected sibling neonates | 41 | 100 | 17 | 25 |
CHB indicates congenital heart block; ND, not determined; SLE, systemic lupus erythematosus.