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Clinical characteristics according to RNF213 genotypes. A, Box plots of age at onset. The blue line connects each average value. B, Differences in clinical characteristics reflecting the disease severity. Compound hetero indicates compound heterozygotes for p.R4810K and the other rare missense variants; HA, presenting headaches only; Homo, homozygotes for p.R4810K; PCA, posterior cerebral artery involvement.
