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. 2015 May 20;4(5):e001925. doi: 10.1161/JAHA.115.001925

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© 2015 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Hemodynamic changes induced by pacing study. Pigs received right atrial pacing (120 bpm) with continuous hemodynamic monitoring. End-diastolic pressure decreased in the control group but increased in the AoB group (P<0.001), suggesting the propensity of the latter to develop congestive heart failure. Although the parameters did not reach statistical significance, changes in dP/dt_max, dP/dt_min, and Tau were smaller in AoB pigs, suggesting limited functional reserve. *P<0.05. AoB indicates aortic banding; bpm, beats per minute; dP/dt_max, peak left ventricular pressure rate of rise; dP/dt_min, peak left ventricular pressure rate of decline; LV, left ventricular; NS, not significant.