Figure 4.

Systemic inflammation in mouse strains with or without stress. A, A flow cytometry gating strategy to identify proinflammatory cells in mouse strains. A representative double staining of CD11c⁺ and CD11b⁺ populations in blood from SJL mice after stress is shown on the left. A right-side histogram shows 2 subpopulations of Ly6C⁺ cells (low-Ly6C^Lo vs high-Ly6C^Hi) that are positive to CD11b⁺. Numbers indicate percentages of positive cells. B, Changes in CD11b⁺Ly6C^Hi cells in spleens from mouse strains. C, Changes in CD11b⁺Ly6C^Hi cells in blood from mouse strains. Values are mean±SEM; *P<0.05 vs CD11b⁺Ly6C^Hi to C3HeB mice, no stress; ^†P<0.05 vs CD11b⁺Ly6C^Hi to SJL mice, no stress (Wilcoxon); n=8 per each experimental group.