Table 8.
Multivariate HRs to Predict Death/Transplant/VAD
| LVEF Only HR (95% CI) | LVEDD Only HR (95% CI) | LV Mass Only HR (95% CI) | LVEF and LVEDD HR (95% CI) | ||
|---|---|---|---|---|---|
| Original (base) models n =834 Event count =271 | LVEF | 0.95 (0.93 to 0.97) P<0.0001 | 0.97 (0.95 to 0.99) P =0.0041 | ||
| LVEDD | 1.40 (1.22 to 1.61) P<0.0001 | 1.29 (1.11 to 1.50) P =0.0009 | |||
| LV mass severe vs normal | 1.18 (0.83 to 1.67) P =0.3603 | ||||
| Additional adjustment for sodium, blood urea nitrogen, creatinine, and ischemic cardionyopathy, n =542 Event count =186 | LVEF | 0.96 (0.93 to 0.98) P =0.0006 | 0.97 (0.94 to 0.99) P =0.0147 | ||
| LVEDD | 1.33 (1.12 to 1.56) P =0.0009 | 1.22 (1.03 to 1.46) P =0.0235 | |||
| LV mass severe vs normal | 1.22 (0.80 to 1.88) P =0.3526 | ||||
| Base models plus device type n =828 Event count =268 | LVEF | 0.95 (0.93 to 0.97) P<0.0001 | 0.97 (0.95 to 0.99) P =0.0049 | ||
| LVEDD | 1.39 (1.21 to 1.60) P<0.0001 | 1.28 (1.10 to 1.49) P =0.0011 | |||
| LV mass severe vs normal | 1.20 (0.84 to 1.72) P =0.3136 |
All models were also adjusted for sex, age, New York Heart Association class, diabetes, hypertension, QRS duration, heart rate, angiotensin-converting enzyme inhibitor use, β-blocker use. HR indicates hazard ratio; LVEF, left ventricular ejection fraction; LVEDD, left ventricular end-diastolic diameter; VAD, ventricular assist device.