Table 12.

Association of the Allelic Score With Baseline IMT in Subjects With Framingham Risk Score >0.20

	Model	Men (n =1653)			Women (n =1777)			P Value Int*
		β	95% CI	P Value	β	95% CI	P Value
CC-IMTmean	Basic	−0.0001	−0.0005 to 0.0002	0.478	0.0003	−0.0002 to 0.0007	0.250	0.268
	Full	−0.0001	−0.0005 to 0.0002	0.489	0.0003	−0.0002 to 0.0007	0.249	0.221
CC-IMTmax	Basic	0.0000	−0.0006 to 0.0005	0.869	0.0004	−0.0003 to 0.0011	0.283	0.435
	Full	0.0000	−0.0006 to 0.0005	0.875	0.0004	−0.0004 to 0.0011	0.344	0.419
Bif-IMTmean	Basic	−0.0007	−0.0013 to −0.0001	0.023	0.0004	−0.0005 to 0.0013	0.388	0.017
	Full	−0.0007	−0.0013 to −0.0001	0.020	0.0003	−0.0006 to 0.0012	0.520	0.020
Bif-IMTmax	Basic	−0.0008	−0.0015 to −0.0001	0.024	0.0005	−0.0006 to 0.0015	0.398	0.019
	Full	−0.0008	−0.0015 to −0.0001	0.026	0.0004	−0.0007 to 0.0015	0.472	0.024

Basic model was adjusted for age and population structure. Full model was adjusted for age, population structure, body mass index, type 2 diabetes mellitus, systolic blood pressure, current smoking, triglycerides, high-density lipoprotein cholesterol, and C-reactive protein. Bif indicates bifurcation of the carotid artery; CC, common carotid artery; IMT, intima-media thickness; IMT_max, highest of all the maximal IMT values obtained from left and right measurements; IMT_mean, average of mean IMT values obtained from left and right measurements; Int, interaction.

^*Sex–allelic score interaction.