Table 3.

Association and Prediction Measures From the 3 Candidate Cox Models for Cardiac Events

	Model 1	Model 2	Model 3
	Hazard Ratio (95% CI)
Age, per y	0.982 (0.959, 1.006)	0.977 (0.954, 1.001)	0.973 (0.950, 0.997)
Diabetes (vs none)	1.785 (1.197, 2.661)	1.623 (1.079, 2.442)	1.590 (1.059, 2.385)
Triglyceride, per 10 mg/dL	1.020 (1.003, 1.037)	1.018 (1.001, 1.035)	1.017 (1.000, 1.033)
CACS 100 to 400 (vs <400)		2.018 (1.180, 3.451)	2.122 (1.236, 3.642)
CACS >400 (vs <400)		2.049 (1.203, 3.489)	2.185 (1.285, 3.715)
Nonculprit CT-HRP (vs none)			2.202 (1.237, 3.918)
Harrell’s C, % (bootstrap SE)*	60.67 (3.36)	63.19 (2.83)	65.81 (2.69)
Two-sided P for c-increment*†		0.336	0.144
Minus-2 times log likelihood	1048.6	1039.4	1033.3
Likelihood ratio P†		0.010	0.049

CACS indicates coronary artery calcium score; CT-HRP, computed tomography–verified high-risk plaque; SE, standard error.

^*Based on 500 bootstrap samples.

^†Comparison between adjacent models using bootstrap SE (Models 1 vs 2 or Models 2 vs 3).