Table 6.

Reclassification Metrics With Addition of LVMI to Traditional Risk Factor Model to Predict Incident CVD

Reclassification Metric	Model for CVD
	CVD Risk Factors	+LVMI	+LVM/LVEDV	+RWT	+LVMI and LVM/LVEDV	+LVMI and RWT
C-statistic value (95% CI)	0.71 (0.65 to 0.77)	0.73 (0.67 to 0.78)	0.72 (0.67 to 0.78)	0.73 (0.67 to 0.78)	0.73 (0.67 to 0.79)	0.74 (0.68 to 0.80)
NRI, categorical (<3%, 3% to 6%, >6%)		0.09 (P=0.03)	0.10 (P=0.01)	0.13 (0.0002)	0.09 (P=0.049)	0.13 (P=0.004)

Columns represent reclassification measures with addition of standardized LVMI, LVM/LVEDV, and RWT each added separately to CVD prediction model containing traditional CVD risk factors only, then added in combination to traditional CVD risk factor model (right-most 2 columns). CVD indicates cardiovascular disease; LVEDV, left ventricular end-diastolic volume; LVM, left ventricular mass; LVMI, left ventricular mass index; NRI, net reclassification improvement index; RWT, relative wall thickness.