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. 2015 Aug 27;4(9):e002192. doi: 10.1161/JAHA.115.002192

Table 3.

Cause of Death and Indication of PPM

PAC ≤76/day PAC >76/day
n=3299 n=2072 P Value
Cause of death
 Infection 40 (1.2) 96 (4.6) <0.001
 Malignancy 63 (1.9) 52 (2.5) 0.348
 CV 129 (3.9) 162 (7.8) <0.001
 HF 7 (0.2) 19 (0.9) <0.001
 MI 30 (0.9) 36 (1.7) 0.015
 SCD 3 (0.1) 13 (0.6) 0.001
 Neurologic 7 (0.2) 11 (0.5) 0.086
Indication of PPM
 SSS 20 (0.6) 58 (2.8) <0.001
 Long pause 16 (0.5) 48 (2.3) <0.001
 Tachy-brady 3 (0.1) 8 (0.4) 0.003
 Bradycardia 1 (0.0) 2 (0.1) 0.563
 AVB 13 (0.4) 23 (1.1) 0.001
 VT 3 (0.1) 1 (0.0) 0.852
 AF or PAF 3 (0.1) 6 (0.3) 0.041

AF indicates atrial fibrillation; AVB, atrioventricular block; CV, cardiovascular; HF, heart failure; MI, myocardial infarction; PAC, premature atrial complex; PAF, paroxysmal atrial fibrillation; PPM, permanent pacemaker; SCD, sudden cardiac death; SSS, sick sinus syndrome; Tachy-brady, tachy-brady syndrome; VT, ventricular tachycardia.