Table 6.
Reclassification Down: % Events (n/N) | Reclassification Up: % Events (n/N) | Relative Risk | P Categorical Reclassification* | P Continuously Graded Reclassification† | |
---|---|---|---|---|---|
ChrIRD | 15.0 (486/3242) | 17.6 (568/3233) | 1.17 | 0.005 | <0.0001 |
CVD | 11.3 (355/3145) | 12.0 (401/3330) | 1.06 | 0.34 | 0.13 |
CHD | 6.0 (190/3187) | 7.1 (233/3288) | 1.18 | 0.07 | 0.25 |
Stroke | 2.9 (88/3028) | 2.4 (84/3447) | 0.83 | 0.24 | 0.19 |
HF | 3.3 (104/3078) | 3.5 (118/3397) | 1.06 | 0.83 | 0.22 |
HDL indicates high-density lipoprotein; ChrIRD, noncancer chronic inflammation–related hospitalization and death; CVD, cardiovascular disease; CHD, coronary heart disease; HF, heart failure.
P based on 2-sample z test for proportions comparing cumulative event rates for those reclassified up versus those reclassified down.
P for graded reclassification (Poisson regression of outcome on reclassification probability adjusted for base probability).