Table 6.
Patient Characteristics Among the Subset of Patients Admitted to Cardiology-Specific ICUs
| Characteristic | LMIV Patients (n=60) | HMIV Patients (n=12 907) | P Value |
|---|---|---|---|
| Demographics | |||
| Age, y | 66±12 | 63±14 | 0.09 |
| Female sex, % | 37 | 33 | 0.56 |
| White race, % | 77 | 81 | 0.38 |
| Body-mass index, kg/m2 | 30±7 | 30±11 | 0.97 |
| Medical history | |||
| Diabetes, % | 22 | 19 | 0.53 |
| Hypertension, % | 23 | 23 | 1.00 |
| Dyslipidemia, % | 18 | 13 | 0.19 |
| Cerebrovascular disease, % | 2 | 1 | 0.46 |
| AMI in past 6 months, % | 7 | 3 | 0.08 |
| Systolic heart failure, % | 18 | 5 | <0.001 |
| Chronic kidney disease, % | 7 | 5 | 0.43 |
| Chronic lung disease, % | 7 | 6 | 0.88 |
| AMI location | |||
| Anterior, % | 20 | 21 | 0.88 |
| Inferior, % | 20 | 33 | 0.027 |
| Non-Q-wave AMI, % | 43 | 33 | 0.09 |
| Objective findings at ICU admission | |||
| Mean blood pressure, mm Hg | 84±18 | 88±17 | 0.045 |
| Heart rate, beats per minute | 86±19 | 78±16 | <0.001 |
| White blood cell count, ×1000/μL | 12±5 | 11±4 | 0.054 |
| Hemoglobin, g/dL | 12±2 | 13±2 | 0.10 |
| Creatinine, mg/dL | 1.3±1 | 1.1±1 | 0.11 |
| Glucose, mg/dL | 148±67 | 146±69 | 0.78 |
| Troponin-I, ng/mL | 25±53 | 35±70 | 0.52 |
| Troponin-T, ng/mL | 3±3 | 5±11 | 0.35 |
| Worst laboratory studies within 72 hours | |||
| Lowest hemoglobin, g/dL | 11±2 | 12±2 | <0.001 |
| Highest creatinine, mg/dL | 1.6±1 | 1.3±1 | 0.033 |
| Highest glucose, mg/dL | 214±96 | 178±92 | 0.003 |
| Peak troponin-I, ng/mL | 27±53 | 44±78 | 0.33 |
| Peak troponin-T, ng/mL | 4±4 | 6±12 | 0.38 |
| Major interventions during first 24 hours | |||
| Thrombolytic therapy, % | 13 | 22 | 0.10 |
| Percutaneous coronary intervention, % | 83 | 75 | 0.15 |
| Endotracheal intubation, % | 28 | 5 | <0.001 |
| Inotropic or pressor support, % | 12 | 5 | 0.009 |
| APACHE-IV | 52±28 | 41±19 | <0.001 |
| APS | 40±26 | 30±17 | <0.001 |
Values are expressed as percentages or mean±standard deviation. AMI indicates acute myocardial infarction; APACHE-IV, Acute Physiology and Chronic Health Evaluation, Fourth Revision; APS, Acute Physiology Score; HMIV and LMIV, high and low annual volume of acute myocardial infarction, respectively; ICU, intensive care unit.