Table 2.
Characteristics of Animal Models in Animal Study 2
| Parameters | Nx/PCS Mice (n=6) | Nx/PCS/Apocynin Mice (n=6) |
|---|---|---|
| EF, % | 64.14±1.86 | 64.64±2.18 |
| FS, % | 34.22±1.36 | 34.89±1.68 |
| IVSd, mm | 0.985±0.055 | 0.981±0.046 |
| LVEDD, mm | 3.50±0.16 | 3.91±0.17 |
| LVPWd, mm | 0.928±0.048 | 0.911±0.038 |
| IVSs, mm | 1.708±0.068 | 1.650±0.090 |
| LVESD, mm | 2.26±0.10 | 2.54±0.11 |
| LVPWs, mm | 1.606±0.081 | 1.574±0.097 |
| LVW/BW, mg/g | 3.68±0.11 | 3.72±0.12 |
| SBP, mm Hg | 139.8±4.5 | 137.5±4.7 |
Values are means±SEM. BW indicates body weight; EF, ejection fraction; FS, fractional shortening; IVSd, interventricular septum diastole; IVSs, interventricular septum systole; LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter; LVPWd, left ventricular posterior wall diastole; LVPWs, left ventricular posterior wall systole; LVW, left ventricle weight; Nx, 5/6 nephrectomy; PCS, p-cresyl sulfate; SBP, systolic blood pressure.