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. Author manuscript; available in PMC: 2015 Oct 9.
Published in final edited form as: Nanotoxicology. 2013 May 28;8(5):485–507. doi: 10.3109/17435390.2013.801089

Figure 7.

Figure 7

rtPCR validation of microarray and Western blot analysis of key proteins driving D-SWCNT and D-MWCNT vs. ASB cell neoplastic-like transformation signalling. A) Comparison of microarray to rtPCR expression of key transformation genes was performed. * indicates those rtPCR values that significantly differed from microarray gene expression. B) Over-expression of several proto-oncogenes associated with D-CNT and ASB cell signalling. C) Decreased tumour suppressor and increased caspase 8 expression in D-SWNCT, D-MWCNT and ASB cells. D) Decreased NF-κB expression in D-CNT cells. E) Over-expressed inflammasome-associated chemokines and a developmental regulator in ASB cells.