Figure 2.

Cell-type-specific differential expression analysis results using csSAM. Each graph shows the dependence between the number of differentially expressed genes (X-axis) and FDR (Y-axis), eg, 68 genes can be detected as differentially expressed in B-cells of SLE patients at FDR <0.5. (A) SAM analysis of differentially expressed genes in heterogeneous matrix; (B) CD3+ T-cell-specific differential expression analysis; (C) monocyte-specific differential expression analysis; (D) neutrophil-specific differential expression analysis; and (E) B-cell-specific differential expression analysis.