Table 2.
Relationships between s-RNY1-5p and classical cardiovascular risk factors in controls and cases
| Controls (n = 514) | Cases (n = 263) | |
|---|---|---|
| Age (years) | −0.07 (0.10) | −0.09 (0.14) |
| School (years of schooling) | 0.01 (0.88) | −0.05 (0.39) |
| Alcohol (g/day) | −0.12 (0.008) | −0.04 (0.50) |
| Tobacco consumption number (pack/year) | 0.04 (0.50) | 0.14 (0.03) |
| Levels of physical activity | −0.01 (0.88) | −0.04 (0.50) |
| Waist (cm) | −0.09 (0.04) | −0.02 (0.80) |
| Body mass index (kg/m2) | −0.07 (0.14) | −0.03 (0.63) |
| Total cholesterol (g/L) | 0.07 (0.11) | 0.11 (0.09) |
| HDL-cholesterol (g/L) | −0.03 (0.53) | −0.02 (0.82) |
| LDL-cholesterol (g/L) | 0.09 (0.05) | 0.12 (0.06) |
| Triglyceride (g/L) | 0.03 (0.52) | 0.01 (0.90) |
| ApoA-I (g/L) | −0.09 (0.04) | −0.08 (0.17) |
| ApoB (g/L) | 0.18 (<0.001) | 0.18 (0.003) |
| Lipoprotein (a) (g/L) | 0.04 (0.39) | 0.07 (0.24) |
| hs-CRP (mg/L) | 0.16 (<0.001) | 0.14 (0.03) |
| Gamma glutamyl transferase (IU/L) | 0.04 (0.41) | 0.11 (0.09) |
| Fasting glucose (mmol/L) | 0.06 (0.22) | −0.04 (0.54) |
| Serum insulin (UI/L) | −0.07 (0.14) | −0.02 (0.81) |
| HOMA-IR | −0.05 (0.24) | −0.05 (0.46) |
| Systolic blood pressure (mmHg) | −0.01 (0.74) | −0.08 (0.19) |
| Resting heart rate (beat/mn) | 0.04 (0.42) | 0.03 (0.64) |
Spearman rank correlation coefficients (P value)
ApoA-I, Apolipoprotein A-I; ApoB, Apolipoprotein B; hs-CRP, High sensitive C-reactive protein; HOMA-IR, Homeostatic model assessment-insulin resistance