Table 6.
Identification of eight additional gene sets for a comparison between immunized zQ175 and immunized wild-type mice (Imm zQ175 > ImmWT)
| Entrez gene Id | Gene symbol | 1 | 2a | 3a | 4 | 5 | 6 | 7 | 8 | 9 | 10 | Gene description |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3553 | IL1B | X | X | X | X | X | X | X | X | X | Interleukin 1, beta | |
| 3569 | IL6 | X | X | X | X | X | X | X | X | X | Interleukin 6 | |
| 4792 | NFKBIA | X | X | X | X | X | X | X | Nuclear factor of kappa-light polypeptide gene enhancer in B cells inhibitor, alpha | |||
| 3557 | IL1RN | X | X | X | X | X | Interleukin 1 receptor antagonist | |||||
| 7128 | TNFAIP3 | X | X | X | X | X | X | Tumor necrosis factor, alpha-induced protein 3 | ||||
| 9034 | CCRL2 | X | X | X | Chemokine (C-C motif) receptor-like 2 | |||||||
| 384 | ARG2 | X | X | Arginase, type II | ||||||||
| 7097 | TLR2 | X | X | X | X | Toll-like receptor 2 | ||||||
| 7124 | TNF | X | X | X | X | X | X | X | Tumor necrosis factor | |||
| 3556 | IL1RAP | X | X | Interleukin 1 receptor accessory protein | ||||||||
| 3458 | IFNG | X | X | X | X | Interferon, gamma | ||||||
| 1154 | CISH | X | X | Cytokine inducible SH2-containing protein | ||||||||
| 9547 | CXCL14 | X | Chemokine (C-X-C motif) ligand 14 | |||||||||
| 57126 | CD177 | X | CD177 molecule |
Immune-related genes from the four leading-edge subsets (Table 3) were grouped and used to probe the entire MSigDB (v5.0). 1: Altemeier response to LPS with mechanical ventilation; 2: Biocarta IL1R; 3: GSE15733 BM versus spleen memory CD4 T cell up; 4: Hallmark TNFA signaling via NFKB; 5: HINATA NFKB targets keratinocyte up; 6: PID IL23; 7: Reactome immune system; 8: MARKS HDAC targets down; 9: KEGG NOD-like receptor signaling; 10: Lindstedt dendritic cell maturation. Asterisk denotes previously identified gene set.
adenotes previously identified gene set.