Table 3.
Comparison of EoE characteristics by pediatric versus adult onset of disease
| Peds. onset (n = 172; 45%) | Adult onset (n = 207; 55%) | p* | |
|---|---|---|---|
| Age (mean years ± SD) | 12.7 ± 11.3 | 35.7 ± 17.1 | -- |
| Adults ≥ 18 years | -- | -- | -- |
| Males (n, %) | 140 (81) | 138 (67) | 0.001 |
| Whites (n, %) | 129 (75) | 176 (85) | 0.02 |
| Symptoms (n, %) | |||
| Dysphagia | 75 (44) | 169 (83) | < 0.001 |
| Food impaction | 35 (21) | 65 (35) | 0.003 |
| Heartburn | 73 (43) | 66 (35) | 0.12 |
| Chest pain | 8 (5) | 25 (13) | 0.005 |
| Abdominal pain | 51 (30) | 32 (17) | 0.004 |
| Nausea | 17 (10) | 21 (11) | 0.72 |
| Vomiting | 62 (37) | 29 (16) | < 0.001 |
| Failure to thrive | 40 (24) | 9 (5) | < 0.001 |
| Symptom length prior to dx (mean years ± SD) | 6.4 ± 8.2 | 8.2 ± 9.7 | 0.10 |
| Atopic diseases (n, %) | |||
| Allergic rhinitis, sinusitis, dermatitis | 36 (39) | 61 (33) | 0.28 |
| Asthma | 51 (31) | 38 (20) | 0.03 |
| Food allergy | 36 (24) | 26 (17) | 0.11 |
| Endoscopic findings (n, %) | |||
| Normal | 47 (28) | 16 (8) | < 0.001 |
| Rings | 33 (19) | 115 (56) | < 0.001 |
| Stricture | 14 (8) | 52 (25) | < 0.001 |
| Narrowing | 13 (8) | 31 (15) | 0.02 |
| Linear furrows | 60 (35) | 90 (44) | 0.08 |
| White plaques | 42 (25) | 39 (19) | 0.19 |
| Decreased vascularity | 38 (22) | 20 (10) | 0.001 |
| Crêpe-paper | 16 (9) | 7 (3) | 0.02 |
| Erosive esophagitis | 42 (25) | 47 (23) | 0.71 |
| Hiatal hernia | 6 (4) | 29 (14) | < 0.001 |
| Dilation performed | 13 (8) | 63 (31) | < 0.001 |
| Max eosinophil count (mean eos/hpf ± SD) | 81.8 ± 69.7 | 88.9 ± 89.4 | 0.40 |
*
p values calculated using a t-test for continuous variables and chi-square for categorical variables.