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SEC-HPLC chromatograms of rhEPO. (A) Native rhEPO solution; (B) RhEPO recovered from the dialysis bag after in vitro release of rhEPO-loaded PEG5000-PLA3900 micelle; (C) RhEPO recovered from the dialysis bag after in vitro release of native rhEPO solution.
Abbreviations: SEC-HPLC, size-exclusion high performance liquid chromatography; rhEPO, recombinant human erythropoietin; PEG–PLA, poly(ethylene glycol)– poly(d,l-lactide).
