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Percentage increase of hemoglobin concentration of the rats after IV administration of rhEPO-loaded PEG–PLA micelles (Table 2, batch 11, 15, and 16), native rhEPO and PBS (2000 IU/kg).
Notes: Each point represents mean ± SD (n = 5); *P < 0.05 (micelle group vs native rhEPO group).
Abbreviations: IV, intravenous; rhEPO, recombinant human erythropoietin; PEG–PLA, poly(ethylene glycol)–poly(d,l-lactide); PBS, phosphate buffered saline; SD, standard deviation.
