Figure 5.

In vitro cytotoxicities of AMB-loaded formulations.
Notes: (A) Hemolysis ratio (%) of free AMB and AMB-loaded formulations. (B) Cytotoxicity of free AMB and AMB-loaded formulations against CCC-HEK-1 cell line with the MTT assay. Data from three independent experiments were expressed as mean ± SEM (n=3).
Abbreviations: AMB, amphotericin B; NP, nanoparticle; OX26, TfR monoclonal antibody of rats; PBS, phosphate-buffered saline; PEG, polyethylene glycol; PLA, poly(lactic acid); SEM, standard error of mean; TfR, transferrin receptor; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide.