Table 3.
Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age | ||||||
---|---|---|---|---|---|---|
Patient or population: Children aged between 6 months and five years | ||||||
Intervention: Vitamin A supplementation | ||||||
Comparison: Placebo or usual care | ||||||
Outcomes | Illustrative comparative risksa (95 % CI) | Relative effect (95 % CI) | No. of Participants (studies) | Quality of the evidence (GRADE) | Comments | |
Diarrhoea-related mortality | Low risk population | RR 0.72; 95 % CI 0.57 to 0.91 | 90,951 (7 studies) | +++O moderate2 | Total number of participants reflects number randomised to studies. The analysis combined cumulative risk and risk per/1000 years follow-up. | |
3 per 10001 | 2 per 1000 (2 to 3) | |||||
Follow-up: 48–104 weeks | Medium risk population | |||||
4 per 10001 | 3 per 1000 (2 to 4) | |||||
High risk population | ||||||
9 per 10001 | 6 per 1000 (5 to 8) |
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