Table 1.

Clinical characteristics of WKYs and SHRs following 22-week treatment

Parameters	WKY-C (n = 10)	SHR-C (n = 10)	SHR-H (n = 10)	SHR-L (n = 10)
Weight (g)	350.55 ± 17.77	345.67 ± 11.63	344.89 ± 15.67	354.63 ± 11.64
BUN (mM)	9.19 ± 2.58	9.21 ± 2.13	9.16 ± 1.36	10.20 ± 1.63
Cr (uM)	32.57 ± 4.65	38.50 ± 17.17	30.00 ± 5.86	34.63 ± 10.42
UP (mg/24 h)	14.47 ± 5.45	39.14 ± 12.91**	23.79 ± 6.26**##	30.16 ± 5.43**#

Data are presented as mean ± SD, n = 10

BUN blood urea nitrogen, Cr serum creatinine, UP 24 h urine protein for 24 h

* P < 0.05, ** P < 0.01 vs. WKY-C group

^# P < 0.05, ^## P < 0.05 vs. SHR-C group