Skip to main content
. 2015 Oct 9;10(10):e0140293. doi: 10.1371/journal.pone.0140293

Table 3. Disease-free survival (DFS) and overall survival (OS) according to the PIK3CA status (Sanger/qPCR).

N 4-year DFS (%) Log-rank p-value 4-year OS (%) Log-rank p-value
All patients 1008 77.1 . 89.3 .
PIK3CAmut 235 81.3 0.99 90.0 0.89
PIK3CAwt 773 75.8 89.1
PIK3CAhel 88 81.4 >0.99 89.5 0.95
PIK3CAkin 147 81.3 90.3
PIK3CAwt 773 75.8 89.1

PIK3CAhel, mutations present in the helical (and kinase) domain; PIK3CAkin, mutations present only in the kinase domain; PIK3CAwt, PIK3CA wild-type; DFS, disease-free survival; OS, overall survival.