Table 3. Disease-free survival (DFS) and overall survival (OS) according to the PIK3CA status (Sanger/qPCR).
N | 4-year DFS (%) | Log-rank p-value | 4-year OS (%) | Log-rank p-value | |
---|---|---|---|---|---|
All patients | 1008 | 77.1 | . | 89.3 | . |
PIK3CAmut | 235 | 81.3 | 0.99 | 90.0 | 0.89 |
PIK3CAwt | 773 | 75.8 | 89.1 | ||
PIK3CAhel | 88 | 81.4 | >0.99 | 89.5 | 0.95 |
PIK3CAkin | 147 | 81.3 | 90.3 | ||
PIK3CAwt | 773 | 75.8 | 89.1 |
PIK3CAhel, mutations present in the helical (and kinase) domain; PIK3CAkin, mutations present only in the kinase domain; PIK3CAwt, PIK3CA wild-type; DFS, disease-free survival; OS, overall survival.