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. 2015 Oct 9;11(10):e1005573. doi: 10.1371/journal.pgen.1005573

Fig 3. Bioinformatic annotation for the APOB locus.

Fig 3

Bioinformatic annotation was undertaken for rs1367117, located within the 4th exon of the APOB gene, using the Epigenome Browser (http://epigenomegateway.wustl.edu/). APOB gene is shown in the blue track and the focal SNP with a vertical bar. Level of DNA methylation (whole genome bisulfite sequencing, or WGBS), histone marks indicative of promoters (H3K4me3) and enhancers (H3K4me1), and expression levels (RNA-seq) were plotted in three relevant tissues: liver, adipose, and small intestine.