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. 2015 Oct 9;9(10):e0004105. doi: 10.1371/journal.pntd.0004105

Table 2. Results of Univariate and Multivariate Linear Regression on eGFR derived by CKD-EPI equation.

Variables Univariate Multivariate
β coefficient (95% CI) P Value β coefficient (95% CI) P Value
Seropositive to Leptospira -4.05 (-4.99, -3.11) <0.001 -3.04 (-4.15, -1.93) <0.001
Age (y) -0.78 (-0.86, -0.69) <0.001 -0.74 (-0.78, -0.71) <0.001
Male -3.06 (-5.67, -0.44) 0.02 -1.49 (-2.73, -0.25) 0.02
Annual income ≥13,000 (US dollars) 4.50 (1.55, 7.46) 0.004 -1.10 (-2.20, 0.00) 0.05
Diabetes Mellitus -14.61 (-17.15, -12.06) <0.001 -2.41 (-4.84, 0.02) 0.05
Hypertension -17.42 (-20.52, -14.32) <0.001 -3.56 (-5.23, -1.90) <0.001
Cardiovascular disease -16.64 (-19.56, -13.72) <0.001 -4.00 (-6.55, -1.46) 0.002
Gout or Hyperuricemia -12.83 (-14.74, -10.92) <0.001 -5.93 (-8.41, -3.45) <0.001
Urinary tract disease -7.79 (-9.89, -5.69) <0.001 0.88 (-1.72, 3.48) 0.5
Chinese herb use -0.79 (-2.86, 1.27) 0.4 -0.60 (-1.96, 0.75) 0.4
Oral analgesic use -0.92 (-3.60, 1.75) 0.5 2.07 (0.20, 3.94) 0.03
Analgesic injection -6.87 (-9.84, -3.89) <0.001 -1.37 (-3.93, 1.19) 0.3
Cigarette smoking -4.68 (-6.03, -3.32) <0.001 -1.30 (-2.76, 0.17) 0.08
Alcohol -3.89 (-5.22, -2.56) <0.001 0.79 (-0.79, 2.35) 0.3
Metabolic syndrome -11.25 (-13.62, -8.88) <0.001 -1.26 (-2.76, 0.24) 0.1