Table 1.

Phenotype of PA patients with secondary adrenal nodules investigated in this study and compared to 172 other PA patients from the COMETE-HEGP cohort.

Parameters	Patients with multinodular adrenals	Other patients	p value
N	27	172
gender F (%)	35	54	0.06
Age of diagnosis (years)	44 (40;58)	40 (34;47)	0.07
Duration of hypertension (years)	3 (1.0;13.5)	4.5 (1.0;8.7)	0.8
Preoperative SBP (mmHG)	147 (138;160)	147 (136;158)	0.5
Preoperative DBP (mmHg)	91 (81;96)	92 (86;102)	0.07
Minimal plasma K (mmol/L)	3.1 (2.6;3.4)	3.1 (2.9;3.4)	0.6
Plasma Aldosterone (pmol/L)	823 (570;1230)	820 (550;1172)	0.9
ARR (pmol/mU)	160 (109;246)	152 (102;217)	0.7
Anti-hypertensive drugs (n)	3 (2;4)	2 (1;3)	0.06
Lateralization index	10 (6.5;28)	19 (10;38)	0.08
APA size (mm)	13 (10;18)	15 (10;20)	0.42
Time of follow up (months)	8.5 (6;13.5)	7 (6;11)	0.07
Post op SBP (mmHG)	131 (125;139)	127 (120;135)	0.06
Post op DBP (mmHG)	82 (77;90)	82 (76;87)	0.6
Post op plasma K (mmol/L)	4.1 (3.9;4.6)	4.1 (3.9;4.4)	0.6
Post op plasma aldosterone (pmol/L)	98 (46;246)	115 (67;229)	0.9
Post op anti-hypertensive drugs (n)	1 (0;2)	0 (0;1)	0.07

SBP: systolic blood pressure; DBP: diastolic blood pressure; ARR: aldosterone to renin ratio