In vivo 5D reconstruction results for the Tie2Cre; p53FL/− mouse (Ref. 45). (A) Energy average reconstruction results at each of ten cardiac phases, including difference images between each phase and the time-averaged reconstruction. Anatomic labels (upper, left): RA, right atrium; LA, left atrium; RV, right ventricle; LV, left ventricle. (B) End diastole at 80 and 40 kVp followed by postreconstruction material decomposition results (red, iodine; green, gold). Arrows denote the center of a perfusion defect caused by partial heart irradiation. CT data and difference images are scaled in Hounsfield units as shown. Iodine and gold concentrations are scaled as shown in mg/ml. Scale bars: 1 cm.